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Preheat your oven to 350º Fahrenheit. Spray your bread pan with a thin layer of cooking spray. Line the pan with parchment paper leaving some overhang for easier removal.
Line the bottom of the pan with a single layer of graham crackers.
Mix the flour, brown sugar, baking powder, cocoa powder, baking soda and salt in a large bowl. Set aside.
Whisk the melted butter, eggs, vanilla extract, hot water, and buttermilk in a separate bowl. Pour the buttermilk mixture into the flour mixture and stir until just combined. The batter might be a little lumpy.
Break apart the remaining graham crackers. Set a few aside for the topping and add the remainder to the bowl. Fold ¾ cup chocolate chips and ¾ cup marshmallows into the batter.
Bake for 1 hour. Use a toothpick to check for doneness.* Cool in the pan for 10 minutes before removing to a cooling rack to cool completely.
Frosting
Beat the softened butter in a medium mixing bowl on high speed until smooth, about 2 minutes. Add the marshmallow creme and vanilla extract and beat on high until smooth and fluffy, about 1 minute.
Add the powdered sugar and continue to beat on high until the marshmallow frosting is smooth.
Spread the marshmallow frosting over the cooled bread. Top with the remaining marshmallows, chocolate chips, and graham cracker pieces. Slice and serve immediately.